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Table 3 Inhibition zone (in mm) of the synthesized compounds compared with standard antibiotic penicillin G against Gram-positive and Gram-negative bacteria at 10−3 g/ml

From: Synthesis, characterization, and in vitro antimicrobial investigation of novel pyran derivatives based on 8-hydroxyquinoline

Compound

Inhibition zone diameter (mm)

Gram-positive bacteria

Gram-negative bacteria

Staphylococcus aureus

Vibrio parahaemolyticus

Escherichia coli

Pseudomonas aeruginosa

Q1 (R = Cl)

35

30

18

Q2 (R = OCH3)

17

10

Q3 (R = NO2)

13

10

Q4 (R = H)

11

5

Penicillin G

11

5

10

9