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Beni-Suef University Journal of Basic and Applied Sciences

Table 4 Effect of IM extract on scopolamine-induced amnesia in Wistar rats

From: Characterization of coumarins from Ipomoea mauritiana Jacq by LC-APCI-MS/MS analysis and evaluation of its anti-amnesic activity

Group

Step through latency (sec)

Step down latency (sec)

Reference

memory error

Working

memory error

Normal (vehicle 10 ml/kg, p.o.)

101.22 ± 12.07

9.05 ± 1.16

4.16 ± 0.75

6.33 ± 1.36

Control (vehicle 10 ml/kg, p.o.)

44.05 ± 8.53#

3.44 ± 1.25#

8.38 ± 1.04#

9.22 ± 2.93#

Rivastigmine (1.5 mg/kg., p.o.)

88.05 ± 17.78*

7.89 ± 2.20*

5.94 ± 1.06*

6.16 ± 1.37*

IM (100 mg/kg., p.o.)

77.33 ± 7.06*

3.72 ± 0.60

7.11 ± 1.43

6.05 ± 0.92*

IM (200 mg/kg., p.o.)

76.61 ± 12.47*

5.44 ± 1.58

7.66 ± 1.72

6.66 ± 1.41*

  1. Values are Mean ± SD, n = 6, #p < 0.05when compared with G1, normal, *p < 0.05 when compared with G2, control
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