Table 2 Proprietary 3D printing drug products
Drug product | Fabrication technique | Dosage Form Characteristics | References |
|---|---|---|---|
Acetaminophen controlled release tablet | Hot melt extrusion | Specific 3D structure with different inner core densities and outer shell thickness. | [52] |
Warfarin fast disintegrating tablet | Powder based method | Highly porous structure which disintegrates very fast in oral cavity. | [53] |
Aripiprazoleoro dispersible films | Fused filament method | Printed film with a porous structure and amorphization of the drug substance. | [54] |
Colon delivery tablet of aminosalicylate (4- ASA and 5-ASA) | Hot melt extrusion | Monolithic controlled release tablet as patient-tailored medicine. | [55] |
Theophylline immediate and extended release tablet | Hot melt extrusion | A combination of different release mechanisms into a single system with digital control of excipients. | [56] |
Fluorescein 3D printing tablet | Fused filament method | Monolithic tablet for personalized dosemedicine and specific release profile. | [36] |
Prednisolone extended release 3D tablet | Fused filament method | Amorphization of prednisolone in formulation/personalized dose medicine. | [57] |
Ritonavir 3D tablet | Hot melt extrusion | Solid dispersion of drug in hydrophilic polymer to improve the drug solubility and bioavailability. | [24] |
3D tablet containing nanocapsule of deflazacort | Fused filament method | Combination of two technology; 3D printing and nanotechnology to create innovative formulation. | [58] |