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Table 2 The minimum required values for a QSAR model to be generally acceptable

From: In silico modeling of tetraoxane-8-aminoquinoline hybrids active against Plasmodium falciparum

R2Coefficient of determination≥ 0.6
P(95%)Confidence interval at 95% confidence level< 0.05
Q2cvCross validation coefficient< 0.5
R2−Q2cvDifference between R2 and Q2cv≤ 0.3
Next. test setMinimum number of external test set≥ 5
cR2pCoefficient of determination for Y-randomization> 0.5