From: In silico modeling of tetraoxane-8-aminoquinoline hybrids active against Plasmodium falciparum
Model | R | R^2 | Q^2 |
---|---|---|---|
Original | 0.98092 | 0.962205 | 0.922252 |
Random 1 | 0.501859 | 0.251863 | − 1.1707 |
Random 2 | 0.414369 | 0.171701 | − 1.10217 |
Random 3 | 0.711928 | 0.506842 | − 0.11473 |
Random 4 | 0.658547 | 0.433684 | − 0.42149 |
Random 5 | 0.596917 | 0.35631 | − 0.73407 |
Random 6 | 0.187802 | 0.03527 | − 0.96639 |
Random 7 | 0.440244 | 0.193815 | − 1.19777 |
Random 8 | 0.315571 | 0.099585 | − 0.6586 |
Random 9 | 0.431688 | 0.186355 | − 0.93619 |
Random 10 | 0.409386 | 0.167597 | − 0.6433 |
Random model parameters | |||
Average r | 0.466831 | ||
Average r^2 | 0.240302 | ||
Average Q^2 | − 0.79454 | ||
cRp^2 | 0.846252 |