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Table 4 Influence of derivatives on cotton pellet granuloma pouch method

From: Synthesis, characterization, and investigation of the anti-inflammatory effect of 2,3-disubstituted quinazoline-4(1H)-one

Group

Group dose

Granuloma dry weight (mg)

% inhibition

Control

1% CMC

46.34 ± 0.32

–

Diclofenac

10

21.72 ± 0.30**

54.20

G1

10

36.47 ± 0.26*

23.18

20

29.44 ± 0.28*

44.25

G2

10

35.17 ± 0.50*

25.84

20

31.35 ± 0.53*

33.90

G3

10

30.00 ± 0.58*

47.29

20

23.39 ± 0.24**

50.68

  1. *p < 0.05, **p < 0.001 when compared with control