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Table 1 Effect of ethanol extracts of propolis of T. fiebrigi (ETP) and S. jujuyensis (ESP) on edema carrageenan-induced rat paw edema

From: In vivo evaluation of pharmacological properties of Argentine stingless bee geopropolis

Group (n = 6)

Dose (mg/kg)

Paw edema vol in ml (Mean ± S.E.)

 

0 h

1 ha

2 ha

3 ha

4 ha

5 ha

6 ha

Control

s.s.

1.42 ± 0.16

1.73 ± 0.15

2.00 ± 0.20

2.32 ± 0.10

2.42 ± 0.36

2.37 ± 0.32

2.13 ± 0.31

Ibuprofen

100

1.40 ± 0.15

1.45 ± 0.15*

1.40 ± 0.10*

1.40 ± 0.10*

1.45 ± 0.15*

1.45 ± 0.05*

1.55 ± 0.15*

ETP

250

1.40 ± 0.13

1.60 ± 0.02

1.80 ± 0.02*

2.28 ± 0.08

2.37 ± 0.32

2.33 ± 0.29

2.07 ± 0.42

 

500

1.40 ± 0.12

1.57 ± 0.06*

1.62 ± 0.03*

1.90 ± 0.10*

2.07 ± 0.23

1.93 ± 0.25*

1.95 ± 0.13*

 

1000

1.42 ± 0.10

1.50 ± 0.02*

1.53 ± 0.06*

1.55 ± 0.05*

1.60 ± 0.10*

1.67 ± 0.12*

1.57 ± 0.06*

ESP

250

1.43 ± 0.10

1.45 ± 0.05*

1.48 ± 0.03*

1.73 ± 0.12*

1.80 ± 0.20*

1.80 ± 0.10*

1.63 ± 0.06*

 

500

1.43 ± 0.15

1.55 ± 0.09*

1.65 ± 0.13*

1.68 ± 0.03*

1.73 ± 0.06*

1.78 ± 0.03*

1.68 ± 0.03*

 

1000

1.42 ± 0.13

1.50 ± 0.09*

1.53 ± 0.08*

1.58 ± 0.08*

1.62 ± 0.03*

1.72 ± 0.08*

1.55 ± 0.05*

  1. Values are expressed in mean ± S.E.M. (n = 6).
  2. s.s. saline solution
  3. *Statistically different from control group: p < 0.05
  4. aTime after carrageenan injection (h)