From: In vivo evaluation of pharmacological properties of Argentine stingless bee geopropolis
Group (n = 6) | Dose (mg/kg) | Paw edema vol in ml (Mean ± S.E.) | ||||||
---|---|---|---|---|---|---|---|---|
0 h | 1 ha | 2 ha | 3 ha | 4 ha | 5 ha | 6 ha | ||
Control | s.s. | 1.42 ± 0.16 | 1.73 ± 0.15 | 2.00 ± 0.20 | 2.32 ± 0.10 | 2.42 ± 0.36 | 2.37 ± 0.32 | 2.13 ± 0.31 |
Ibuprofen | 100 | 1.40 ± 0.15 | 1.45 ± 0.15* | 1.40 ± 0.10* | 1.40 ± 0.10* | 1.45 ± 0.15* | 1.45 ± 0.05* | 1.55 ± 0.15* |
ETP | 250 | 1.40 ± 0.13 | 1.60 ± 0.02 | 1.80 ± 0.02* | 2.28 ± 0.08 | 2.37 ± 0.32 | 2.33 ± 0.29 | 2.07 ± 0.42 |
500 | 1.40 ± 0.12 | 1.57 ± 0.06* | 1.62 ± 0.03* | 1.90 ± 0.10* | 2.07 ± 0.23 | 1.93 ± 0.25* | 1.95 ± 0.13* | |
1000 | 1.42 ± 0.10 | 1.50 ± 0.02* | 1.53 ± 0.06* | 1.55 ± 0.05* | 1.60 ± 0.10* | 1.67 ± 0.12* | 1.57 ± 0.06* | |
ESP | 250 | 1.43 ± 0.10 | 1.45 ± 0.05* | 1.48 ± 0.03* | 1.73 ± 0.12* | 1.80 ± 0.20* | 1.80 ± 0.10* | 1.63 ± 0.06* |
500 | 1.43 ± 0.15 | 1.55 ± 0.09* | 1.65 ± 0.13* | 1.68 ± 0.03* | 1.73 ± 0.06* | 1.78 ± 0.03* | 1.68 ± 0.03* | |
1000 | 1.42 ± 0.13 | 1.50 ± 0.09* | 1.53 ± 0.08* | 1.58 ± 0.08* | 1.62 ± 0.03* | 1.72 ± 0.08* | 1.55 ± 0.05* |