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Table 2 Effects of ethanol extracts of propolis of T. fiebrigi (ETP) and S. jujuyensis (ESP) on cotton pellet-induced granuloma formation in rats

From: In vivo evaluation of pharmacological properties of Argentine stingless bee geopropolis

Cotton pellet-induced granuloma formation

 

Dose

Transudative

Granuloma

Granuloma

Dry thymus

Groups (n = 6)

(mg/kg/d)

weight (mg)

weight (mg)

inhibition (%)

weight (mg/100 g BW)

Control

ss

594.35 ± 25.60

156.70 ± 3.30

30.49 ± 2.06

Ibuprofen

100

178.90 ± 15.50*

76.20 ± 2.80*

45.56

33. 24 ± 5.40

Meprednisone

5

165.10 ± 14.85*

55.80 ± 9.00*

57.10

22.61 ± 3.95*

ETP

500

357.40 ± 86.60*

86.00 ± 4.90*

45.12

32.50 ± 6.50

 

1000

368.50 ± 34.10*

76.75 ± 8.05*

51.02

33.43 ± 4.30

ESP

500

427.00 ± 42.00*

99.60 ± 5.30*

36.43

34.15 ± 3.50

 

1000

384.50 ± 52.60*

84.90 ± 18.90*

45.80

33.81 ± 3.80

  1. Values are expressed as mean ± S.E.M. (n = 6).
  2. TrW transudative weight, GrW granuloma weight, GI granuloma inhibition, BW body weight, TW thymus weight, ss saline solution
  3. *Significantly different from the control group, p < 0.05