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Table 2 Effects of ethanol extracts of propolis of T. fiebrigi (ETP) and S. jujuyensis (ESP) on cotton pellet-induced granuloma formation in rats

From: In vivo evaluation of pharmacological properties of Argentine stingless bee geopropolis

Cotton pellet-induced granuloma formation
 DoseTransudativeGranulomaGranulomaDry thymus
Groups (n = 6)(mg/kg/d)weight (mg)weight (mg)inhibition (%)weight (mg/100 g BW)
Controlss594.35 ± 25.60156.70 ± 3.3030.49 ± 2.06
Ibuprofen100178.90 ± 15.50*76.20 ± 2.80*45.5633. 24 ± 5.40
Meprednisone5165.10 ± 14.85*55.80 ± 9.00*57.1022.61 ± 3.95*
ETP500357.40 ± 86.60*86.00 ± 4.90*45.1232.50 ± 6.50
 1000368.50 ± 34.10*76.75 ± 8.05*51.0233.43 ± 4.30
ESP500427.00 ± 42.00*99.60 ± 5.30*36.4334.15 ± 3.50
 1000384.50 ± 52.60*84.90 ± 18.90*45.8033.81 ± 3.80
  1. Values are expressed as mean ± S.E.M. (n = 6).
  2. TrW transudative weight, GrW granuloma weight, GI granuloma inhibition, BW body weight, TW thymus weight, ss saline solution
  3. *Significantly different from the control group, p < 0.05