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Table 4 Molecular structure of phthalazinone with substitution of phenyl moiety and their biological activity

From: Molecular docking and QSAR theoretical model for prediction of phthalazinone derivatives as new class of potent dengue virus inhibitors

SN R p IC50
15 4-OCH3 5.712198
16 4-CN 6.154902
17 4-CF3 5.832683
18 3-F 5.821023
19 3-OCH3 6.522879
20 3-CN 5.764472
21 3-CF3 6.886057
22 2-F 5.879426
23 2-OCH3 5.853872
24 2-CN 5.258061
25 2-CF3 5.701147