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Table 5 Minimum suggested value of authentication parameters for a generally satisfactory QSAR model

From: Molecular docking and QSAR theoretical model for prediction of phthalazinone derivatives as new class of potent dengue virus inhibitors

Symbol Name Value
R2 Coefficient of determination ≥ 0.6
P (95%) Confidence interval at 95% confidence level < 0.05
Q2CV Cross validation coefficient > 0.5
R2Q2CV Difference between R2 and Q2CV ≤ 0.3
Next. test set Minimum number of an external test set ≥ 5
cR\( {\displaystyle \begin{array}{c}2\\ {}p\end{array}} \) Coefficient of determination for Y-randomization > 0.5