Effect of epigallocatechin gallate on aluminum chloride-induced changes in behavior, biochemical parameters, and spermatogenesis of Sprague-Dawley rats

Beni-Suef University Journal of Basic and Applied Sciences

Table 1 Effect of EGCG on biochemical parameters of the rats

Group	Glucose (mmol/L)	AST (U/L)	ALT (U/L)	ALP (U/L)	Urea (mg/dL)	Creatinine (mg/dL)
Control	5.8 ± 0.28	83.6 ± 2.70	47.1 ± 3.91	104.33 ± 6.01	20.33 ± 1.49	0.29 ± 0.01
AlCl₃	8.05 ± 0.50*	113.33 ± 9.00*	76.1 ± 8.40*	125.83 ± 9.76	38.0 ± 2.98***	0.437 ± 0.04**
Vitamin C	5.93 ± 0.29	78.17 ± 5.59	51.17 ± 5.71	103.67 ± 6.18	21.6 ± 1.33	0.26 ± 0.02
EGCG	5.83 ± 0.23	87.83 ± 3.83	48.33 ± 3.11	110.33 ± 5.89	21.33 ± 1.76	0.32 ± 0.01
AlCl₃ + vitamin C	6.78 ± 0.69	80.83 ± 4.44	46.83 ± 4.70	106.33 ± 3.48	22.83 ± 2.40	0.327 ± 0.02
AlCl₃ + EGCG	8.55 ± 0.72**	122.67 ± 11.38**	82.67 ± 6.17**	127.17 ± 7.33	40.33 ± 2.51***	0.483 ± 0.01***

Values are expressed as mean ± SEM (n = 6). *P < 0.05, **P < 0.01, and ***P < 0.001 compared with control (one-way ANOVA followed by Tukey’s post-hoc test)