Calotropis gigantea assisted green synthesis of nanomaterials and their applications: a review

Patil, Shriniwas P.

doi:10.1186/s43088-020-0036-6

Beni-Suef University Journal of Basic and Applied Sciences

Table 1 Pharmacological activities of C.gigantea

From: Calotropis gigantea assisted green synthesis of nanomaterials and their applications: a review

Part of plant	Pharmacological Activity	Pharmacological model used	Reference
Flowers	Analgesic	Acetic acid induced writhing	[15]
Flowers	Anti-tumoric	Ehrlich’s ascites carcinoma in mice	[16]
Latex	Antibacterial	Agar well diffusion method using cariogenic bacteria	[17]
Leaves	Antibacterial	Agar well diffusion method using Klebsiella spp	[18]
Flowers	Anti-fungal	Disc diffusion assay method using Aspergillus flavus and Aspergillus fumigatus	[10]
Flowers	Cytotoxicity	Brine shrimp lethality bioassay	[10]
Aerial parts	Antipyretic	TAB (typhoid) vaccine-induced pyrexia in rabbits and Brewer’s yeast-induced pyrexia in rats	[19]
Root bark	Antitumour	Ehrlich’s ascites carcinoma in mice	[20]
Peeled roots	Anticonvulsant and skeletal muscle relaxant activity	Pentobarbitone-induced sleeping time model and rotating rod model	[21]
Leaves	Anticonvulsant and skeletal muscle relaxant activity	Maximal electroshock seizure (MES) and Strychnine-induced convulsions models and rotating rod model	[22]
Leaves	Cytostatic and cytotoxic activity	SRB assay using tumour cell lines: MDA-MB-231 (human breast cancer), PC-3 (human prostate cancer), MCF7 (human breast cancer), HT-29 (human colon cancer), 4 T1 (mouse mammary cancer), and RAW-267 (mouse leukemic monocyte macrophage)	[23]
Leaves	Antiplasmodial	Lactate dehydrogenase assay using human blood	[24]
Latex and fruits	HIF-1 inhibitory activities	T47D cell-based dual-luciferase reporter assay	[25]
Root bark	Wound healing	Excision, incision and dead space wound models	[26]
Roots	Pregnancy interception	Postcoital contraceptive efficacy evaluation	[27]
Latex	Procoagulant activity	Re-calcification time and fibrinogenolytic activity	[28]

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