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Table 4 Phytochemical components of Varthemia candicans ethanolic extract as identified by GC-MS analysis

From: Characterization, antioxidant, and cytotoxic effects of some Egyptian wild plant extracts

Peak no.

RT

Compound name

Area %

Molecular formula

Class

Reported bioactivity

References

1

16.66

2,5-Octadecadienoic acid, methyl ester

3.01

C19H30O2

Fatty acid

No activity reported

 

2

16.83

Megastigma-4,6(E),8(Z)-triene

1.90

C13H20

Alkene

No activity reported

 

3

17.26

9,12-Octadecadienoic acid (Z,Z)-

25.65

C18H32O2

Fatty acid

-Antitumor

-Anti-inflammatory, hypocholesterolemic, hepatoprotective, nematicide, 5-alpha reductase inhibitor, antihistaminic, antiacne, antieczemic, antiandrogenic, antiarthritic, anticoronary, and insect repellant

[26]

4

18.13

7,10,13-Eicosatrienoic acid, methyl ester

0.63

C21H36O2

Fatty acid

No activity reported

 

5

18.66

13-Heptadecyn-1-ol

1.66

C17H32O

Fatty alcohol

Anti-inflammatory and antifungal

[27]

6

18.81

Stigmast-5-en-3-ol, (3á)-

0.43

C29H50O

Phytosterol

Antidiabetic and anti-hypercholesterolemic

[28]

7

19.21

1-Heptatriacotanol

5.21

C37H76O

Fatty alcohol

-Anti-hypercholesterolemic

-Antimicrobial

[29]

[30]

8

19.41

Cholestan-3-ol, 2-methylene-, (3á,5à)-

0.90

C28H48O

Sterol

Antimicrobial anti-inflammatory, anticancer, diuretic, antiasthma, and antiarthritic

[26]

9

21.23

Hexadecatrienoic acid, methyl ester

3.80

C17H28O2

Fatty acid

-Cardio-protective

-Antimicrobial, antioxidant, and anti-inflammatory

[26]

[31]

10

21.29

Cis-9-octadecenoic acid

7.60

C18H34O2

Fatty acid

Cancer preventive flavor, hypocholesterolemic, 5-alpha reductase inhibitor, antiandrogenic, perfumery insectifuge, anti-inflammatory, anemiagenic, and dermatitigenic choleretic

[26]

11

22.02

8,11,14-Docosatrienoic acid, methyl ester

2.71

C23H40O2

Fatty acid

No activity reported

 

12

23.61

ç-Isosparteine

1.28

C15H26N2

Alkaloid

Antimicrobial

[32]

13

24.53

Fischeroside C

2.29

C28H40O12

Diterpene

Antiviral

[33]

14

26.54

Lycopene

0.62

C40H56

Carotenoid

Anti-inflammatory, antioxidant, anti-allergic, and anticancer

-Anti-autophagic and antiapoptotic substance

[34]

[35]

15

27.38

Stigmastan-3,5-diene

2.02

C29H48

Sterol

Antimicrobial

[36]

16

28.17

1-Methyl-3-(3,4-dimethoxyphenyl)-6,7-dimethoxyisochromene

2.90

C20H22O5

Benzopyran derivative

Anti-hypertension, anti-cardiac ischemia, arrhythmia treatment, smooth muscle relaxation, antidiabetic, cardio-protective and anti-angiogenic

[37]

17

29.45

Panaxatriol

25.88

C30H52O4

Triterpene sapogenin

Protect against ischemia and reperfusion injuries

[38]

18

29.82

9,12,15-Octadecatrienoic acid, 2-[(trimethylsilyl)oxy]-1-[[(trimethylsilyl)oxy]methyl]ethyl ester, (Z,Z,Z)-

1.67

C27H54O4Si2

Fatty acid

Antimicrobial, anticancer, hepatoprotective, anti-arthritic, anti-asthma, and diuretic

[26]

19

29.98

9-Octadecenoic acid (Z)-, 9-hexadecenyl ester, (Z)-

0.92

C34H64O2

Fatty acid

No activity reported

 

20

31.52

3à,5à-Cyclo-ergosta-7,9(11),22t-triene-6á-ol

3.25

C28H42O

Steroid

Antitumor and anti-angiogenic

[39]

21

31.98

Trisiloxane, 1,1,1,5,5,5-hexamethyl-3-(4-methylpentyl)-3-[(trimethylsilyl)oxy]-

0.38

C15H40O3Si4

Siloxane derivative

No activity reported

 

22

32.37

1,1,3,3,5,5,7,7,9,9,11,11-Dodecamethyl-hexasiloxane

0.83

C12H38O5Si6

Siloxane derivative

Antimicrobial, antiseptic, hair conditioning agent, skin-conditioning agent-emollient and solvent

[26]

23

32.79

1,1,3,3,5,5,7,7,9,9-Decamethyl-pentasiloxane

2.87

C10H32O4Si5

Siloxane derivative

No activity reported

 

24

33.26

Oleic acid,3-(octadecyloxy)propyl ester

1.59

C39H76O3

Fatty acid

Anti-fungal

[40]

  1. RT retention time (min)