Concentrations (µg mL−1) | Cell viability % ± SD | |||||
---|---|---|---|---|---|---|
Hep3B cells | HepG2 cells | |||||
24 h | 48 h | 72 h | 24 h | 48 h | 72 h | |
Control | 100 ± 0.00 | 100 ± 0.00 | 100 ± 0.00 | 100 ± 0.00 | 100 ± 0.00 | 100 ± 0.00 |
Solvent control (DMSO) | 98.96 ± 0.039 | 97.97 ± 0.063 | 97.27 ± 0.058 | 95.89 ± 0.076 | 95.49 ± 0.052 | 95.25 ± 0.066 |
Farmorubucin, 40 | 1.06 ± 0.014* | 0 ± 0.000* | 0 ± 0.000* | 1.49 ± 0.013* | 0.20 ± 0.002* | 0 ± 0.000* |
25 | 93.61 ± 0.138 | 102.13 ± 0.189 | 105.40 ± 0.264 | 95.61 ± 0.296 | 94.49 ± 0.115 | 92.23 ± 0.484 |
50 | 93.25 ± 0.155 | 111.24 ± 0.051 | 118.33 ± 0.071* | 102.87 ± 0.215 | 100.09 ± 0.028 | 96.15 ± 0.089 |
100 | 89.76 ± 0.057 | 117.39 ± 0.041* | 123.99 ± 0.123* | 111.36 ± 0.123 | 102.71 ± 0.045 | 94.79 ± 0.121 |
150 | 104.14 ± 0.097 | 118.08 ± 0.016* | 126.72 ± 0.040* | 105.64 ± 0.035 | 100.34 ± 0.077 | 91.43 ± 0.037 |
200 | 105.80 ± 0.178 | 127.00 ± 0.134* | 131.03 ± 0.061* | 104.59 ± 0.133 | 93.19 ± 0.092 | 86.87 ± 0.521 |
400 | 108.03 ± 0.066 | 128.01 ± 0.028* | 132.42 ± 0.100* | 99.59 ± 0.030 | 91.77 ± 0.039 | 82.53 ± 0.145* |
500 | 112.31 ± 0.144 | 128.48 ± 0.071* | 133.43 ± 0.211* | 97.90 ± 0.042 | 88.56 ± 0.216 | 67.05 ± 0.031* |