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Table 2 The effect of A. andrachne methanol extract on the viability of Hep3B and HepG2 cells

From: Evaluation of the antioxidant and cytotoxic potency of Euphorbia rigida and Arbutus andrachne methanol extracts in human hepatocellular carcinoma cell lines in vitro

Concentrations (µg mL−1)

Cell viability % ± SD

Hep3B cells

HepG2 cells

24 h

48 h

72 h

24 h

48 h

72 h

Control

100 ± 0.00

100 ± 0.00

100 ± 0.00

100 ± 0.00

100 ± 0.00

100 ± 0.00

Solvent control (DMSO)

98.96 ± 0.039

97.97 ± 0.063

97.27 ± 0.058

95.89 ± 0.076

95.49 ± 0.052

95.25 ± 0.066

Farmorubucin, 40

1.06 ± 0.014*

0 ± 0.000*

0 ± 0.000*

1.49 ± 0.013*

0.20 ± 0.002*

0 ± 0.000*

25

93.61 ± 0.138

102.13 ± 0.189

105.40 ± 0.264

95.61 ± 0.296

94.49 ± 0.115

92.23 ± 0.484

50

93.25 ± 0.155

111.24 ± 0.051

118.33 ± 0.071*

102.87 ± 0.215

100.09 ± 0.028

96.15 ± 0.089

100

89.76 ± 0.057

117.39 ± 0.041*

123.99 ± 0.123*

111.36 ± 0.123

102.71 ± 0.045

94.79 ± 0.121

150

104.14 ± 0.097

118.08 ± 0.016*

126.72 ± 0.040*

105.64 ± 0.035

100.34 ± 0.077

91.43 ± 0.037

200

105.80 ± 0.178

127.00 ± 0.134*

131.03 ± 0.061*

104.59 ± 0.133

93.19 ± 0.092

86.87 ± 0.521

400

108.03 ± 0.066

128.01 ± 0.028*

132.42 ± 0.100*

99.59 ± 0.030

91.77 ± 0.039

82.53 ± 0.145*

500

112.31 ± 0.144

128.48 ± 0.071*

133.43 ± 0.211*

97.90 ± 0.042

88.56 ± 0.216

67.05 ± 0.031*

  1. Data are the mean ± SD of three separate determinations. Means with an asterisk in the same line indicate a significant (p < 0.05) difference between the concentrations tested. Means with asterisks in the same column indicate the significant (p < 0.05) difference between the solvent used