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Table 4 Relation between the concentrations of AgNPs and MIC values of antibiotics among ESBL producing K. pneumoniae isolates

From: Combination of silver nanoparticles with ineffective antibiotics against extended spectrum beta-lactamases producing isolates at Alexandria Main University Hospital, Egypt

Antibiotics (MICs) MIC of silver in combination
Ag/2 Ag/4 Ag/8 Ag/16
No. (%) No. (%) No. (%) No. (%)
Ampicillin
S (≤ 8 µg/ml) 6 (75.00%) 5 (62.50%) 0 (00.00%) 0 (00.00%)
I (= 16 µg/ml) 0 (00.00%) 1 (12.50%) 5 (62.50%) 1 (12.50%)
R (≥ 32 µg/ml) 2 (25.00%) 2 (25.00%) 3 (37.50%) 7 (87.50%)
Cefotaxime
S (≤ 1 µg/ml) 7 (87.50%) 7 (87.50%) 1 (12.50%) 0 (00.00%)
I (= 2 µg/ml) 1 (12.50%) 1 (12.50%) 6 (75.00%) 2 (25.00%)
R (≥ 4 µg/ml) 0 (00.00) 0 (00.00%) 1 (12.50%) 6 (75.00%)
Ceftazidime
S (≤ 4 µg/ml) 7 (87.50%) 7 (87.50%) 1 (12.50%) 0 (0.00%)
I (= 8 µg/ml) 1 (12.50%) 1 (12.50%) 5 (62.50%) 1 (12.50%)
R (≥ 16 µg/ml) 0 (00.00%) 0 (00.00%) 2 (25.00%) 7 (87.50%)
Ciprofloxacin
S (≤ 0.06 µg/ml) 6 (75.00%) 6 (75.00%) 1 (12.50%) 0 (00.00%)
I (0.12–0.5 µg/ml) 2 (25.00%) 2 (25.00%) 5 (62.50%) 3 (37.50%)
R (≥ 1 µg/ml) 0 (00.00%) 0 (0.00%) 2 (25.00%) 5 (62.50%)