Sirtuin-1 in Egyptian patients with coronary artery disease

Beni-Suef University Journal of Basic and Applied Sciences

Table 1 Demographic and biochemical data of the studied groups

	Control	CCS	Unstable angina	AMI	p
Age (years)	51.45 ± 5.32	53.5 ± 6.25	54.71 ± 4.27	57.14 ± 4.01	0.081
Sex (M/F)	11/9	2/4	2/5	2/5	0.45
Hemoglobin (gm/dL)	13.52 ± 1.93	14.21 ± 2.08	14.32 ± 1.81	13.61 ± 1.97	0.74
PLT (cells × 10³/uL)	264.05 ± 80.29	239.5 ± 71.57	237.14 ± 59.64	92.85 ± 16.03©℗∞	0.001**
WBCs (cells × 10³/uL)	6.62 ± 2.41	8.25 ± 2.21	7.41 ± 2.25	12.7 ± 1.68©℗∞	< 0.001**
Cholesterol (mg/dL)	125.2 ± 15.98	189.5 ± 7.17©	171.42 ± 19.3©℗	188.57 ± 11.07©∞	< 0.001**
TG (mg/dL)	71.9 ± 22.74	136 ± 12.08©	140.14 ± 8.41©	144 ± 4.86©	< 0.001**
HDL (mg/dL)	61 ± 12.35	38.66 ± 7.03©	37.57 ± 7.36©	32.14 ± 5.66©	< 0.001**
LDL (mg/dL)	83.6 ± 25.14	122.5 ± 15.59©	129.85 ± 11.18©	133.57 ± 10.69©	< 0.001**
RBS (mg/dL)	117.1 ± 17.56	127.33 ± 12.32	124.57 ± 13.4	122.57 ± 15.95	0.477
Urea (mg/dL)	11.65 ± 5.03	11.66 ± 2.16	14.14 ± 3.89	21.42 ± 2.57©℗∞	< 0.001**
Blood Urea Nitrogen (mg/dL)	6.05 ± 2.12	6.16 ± 1.16	7.14 ± 1.95	10.71 ± 1.49©℗∞	< 0.001**
Creatinine (mg/dL)	0.83 ± 0.18	0.98 ± 0.14	0.9 ± 0.19	1.04 ± 0.15	0.054
CK-MB (ug/L)	8.9 ± 1.01	3.83 ± 1.28©	20.57 ± 8.25©℗	187.42 ± 11.16©℗∞	< 0.001**
SIRT1(ng/mL)	5.99 ± 6.23	3.77 ± 5.62©	1.01 ± 1.58©℗	1.03 ± 1.52131©℗	0.04*

CCS: chronic coronary syndrome; UA: unstable angina; AMI: acute myocardial infarction; PLT: platelet count; WBCs: white blood cells; TG: triglycerides; HDL: high-density lipoprotein; LDL: low-density lipoprotein; RBS: random blood sugar; CK-MB: creatine kinase-MB; SIRT1: sirtuin1; *: p < 0.05: statistically significant; **: p < 0.001: highly statistically significant; ©: significant difference with control; ℗: significant difference with CCC; ∞: significant difference with UA