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Table 1 In vitro antibacterial activity of Icacina trichantha leaves Extracts

From: Stigmasterol and β-Sitosterol: Antimicrobial Compounds in the Leaves of Icacina trichantha identified by GC–MS

Extracts

Microorganism/zone of inhibition (mm) ± SD

Conc. (mg/ml)

Staphylococcus aureus

Escherichia coli

Bacillus subtilis

Pseudomonas aeruginosa

Salmonella typhi

Klebsiella pneumonia

ICLHE

200

28.0 ± 0.82a

23.7 ± 0.47a

24.6 ± 0.94a

19.7 ± 0.47a

18.0 ± 0.82a

15.7 ± 0.47a

 

100

24.0 ± 0.82b

22.3 ± 0.47b

19.7 ± 0.47b

18.0 ± 0.82b

16.7 ± 0.94a

13.7 ± 0.47b

 

50

22.0 ± 0.47c

17.7 ± 0.47c

18.0 ± 0.82c

14.7 ± 0.47c

14.7 ± 0.94a

12.0 ± 0.82c

 

25

17.5 ± 0.47d

16.0 ± 0.82d

13.6 ± 0.47d

12.7 ± 0.47d

11.7 ± 0.47b

9.0 ± 0.47d

 

12.5

14.6 ± 0.47e

13.6 ± 0.47e

11.3 ± 0.47e

10.3 ± 0.47e

11.0 ± 0.82b

 

6.25

12.0 ± 0.82e

11.0 ± 0.82e

10.0 ± 0.82e

ICLEE

200

18.7 ± 0.94a

15.0 ± 1.41a

13.3 ± 0.94a

14.0 ± 0.82a

14.0 ± 0.82a

14.0 ± 0.82a

 

100

13.7 ± 0.94b

13.3 ± 0.47a

13.0 ± 0.82a

12.7 ± 0.94a

11.3 ± 0.94b

11.3 ± 0.47b

 

50

12.3 ± 0.94b

11.7 ± 0.47b

9.3 ± 0.94b

9.7 ± 0.47b

9.7 ± 0.47b

9.7 ± 0.47c

 

25

10.0 ± 0.82c

10.3 ± 0.47c

 

12.5

 

6.25

ICLME

200

19.7 ± 0.47a

17.3 ± 0.94a

15.0 ± 1.41a

16.3 ± 0.47a

15.3 ± 0.94a

16.0 ± 0.82a

 

100

17.0 ± 0.82b

16.3 ± 0.47a

14.0 ± 0.82a

14.0 ± 0.82b

14.0 ± 0.82a

13.0 ± 0.82b

 

50

13.7 ± 0.47c

14.0 ± 0.82b

11.3 ± 0.94b

11.3 ± 0.94c

11.7 ± 0.47b

11.3 ± 0.47c

 

25

10.7 ± 0.94d

13.3 ± 0.94b

10.0 ± 0.82b

10.7 ± 0.94c

10.7 ± 0.94b

9.7 ± 0.47d

 

12.5

9.3 ± 0.94c

 

6.25

Control

 − ve

Gentamicin

10

40

38

38

38

38

40

  1. ICLHE-Hexane Extract of I. trichantha leaves; ICLEE-Ethylacetate Extract of I. trichantha leaves; ICLME-Methanol Extract I. trichantha leaves; – No Activity; concentrations with different superscripts are significantly different for each extract (p < 0.05)