Table 8 Post-compression parameters of batches (F1 to F9) using factorial design
Code | Diameter (mm)** | Thickness (mm)** | Hardness (kg/cm2)* | Friability (%)* | Weight variation (%) | Drug content (%w/w) |
|---|---|---|---|---|---|---|
F1 | 9.0 ± 0.0 | 3.18 ± 0.14 | 5.8 ± 0.25 | 0.41 ± 0.05 | ± 2.11 | 99.81 ± 1.4 |
F2 | 9.0 ± 0.0 | 3.16 ± 0.12 | 5.7 ± 0.27 | 0.31 ± 0.08 | ± 2.16 | 99.67 ± 1.7 |
F3 | 9.0 ± 0.0 | 3.15 ± 0.12 | 5.5 ± 0.44 | 0.36 ± 0.03 | ± 2.02 | 98.75 ± 0.5 |
F4 | 9.0 ± 0.0 | 3.28 ± 0.11 | 5.6 ± 0.41 | 0.37 ± 0.01 | ± 2.75 | 99.47 ± 1.3 |
F5 | 9.0 ± 0.0 | 3.13 ± 0.10 | 5.7 ± 0.27 | 0.36 ± 0.08 | ± 2.46 | 99.87 ± 0.5 |
F6 | 9.0 ± 0.0 | 3.23 ± 0.16 | 5.8 ± 0.62 | 0.28 ± 0.06 | ± 1.85 | 98.38 ± 0.8 |
F7 | 9.0 ± 0.0 | 3.18 ± 0.14 | 5.8 ± 0.37 | 0.41 ± 0.03 | ± 1.89 | 97.01 ± 1.7 |
F8 | 9.0 ± 0.0 | 3.21 ± 0.14 | 5.7 ± 0.44 | 0.36 ± 0.12 | ± 1.86 | 99.24 ± 0.6 |
F9 | 9.0 ± 0.0 | 3.20 ± 0.16 | 5.4 ± 0.27 | 0.22 ± 0.06 | ± 3.75 | 99.04 ± 0.1 |
C1 a | 9.0 ± 0.0 | 3.19 ± 0.12 | 5.9 ± 0.11 | 0.32 ± 0.14 | ± 2.30 | 98.90 ± 0.14 |
C2 a | 9.0 ± 0.0 | 3.24 ± 0.23 | 5.6 ± 0.23 | 0.39 ± 0.02 | ± 2.29 | 99.07 ± 0.13 |
C3 a | 9.0 ± 0.0 | 3.22 ± 019 | 5.8 ± 016 | 0.29 ± 0.11 | ± 3.12 | 99.71 ± 0.51 |