Table 2 Cardiovascular Drugs under BCS classification

1

ACE inhibitors

(a) Benazepril

Class 1

Class 1

High/high

(b) Captopril

Class 3

Class 3

High/low

(c) Cilazapril

Class 3

Class 3

High/low

(d) Enalapril

Class 1

Class 1

High/high

(e) Imidapril

Class 1

Class 3

High/low

(f) Lisinopril

Class 3

Class 3

High/low

(g) Perindopril

Class 3

Class 1

High/low

(h) Quinapril

Class 1

Class 1

High/high

(i) Ramipril

Class 1

Class 1

High/high

(j) Temocapril

Class 1

Class 1

High/high

2

Angiotensin II receptor antagonists

(a) Candesartan cilexetil

Class 2

Class 2

Low/high

(b) Eprosartan

Class 2

Class 2

Low/high

(c) Irbesartan

Class 2

Class 2

Low/high

(d) Losartan

Class 3

Class 3

High/low

(e) Telmisartan

Class 2

Class 2

Low/high

(f) Valsartan

Class 2

Class 2

Low/high

3

Antiadrenergic agents

(a) Carvedilol

Class 2

Class 2

Low/high

(b) Clonidine

Class 3

Class 3

High/low

(c) Doxazosin

Class 1

Class 1

High/high

(d) Reserpine

Class 1

Class 1

High/high

(e) Terazosin

Class 1

Class 3

High/low

4

Antiarrhythmics

(a) Mexiletine

Class 1

Class 1

High/high

(b) Pilsicainide

Class 1

Class1

High/high

5

Antiplatelet Agents

(a) Cilostazol

Class 2

Class 2

Low/high

(b) Clopidogrel

Class 2

Class2

Low/high

(c) Ethyl icosapentate

Class 2

Class2

Low/high

(d) Sarpogrelate hydrochloride

Class 1

Class1

High/high

(e) Ticlopidine

Class 2

Class2

Low/high

(f) Triflusal

Class 2

Class2

Low/high

(g) Warfarin

Class 2

Class2

Low/high

6

Antihyperlipidemics

(a) Ezetimibe

Class 2

Class 2

Low/high

(b) Fenofibrate

Class 2

Class 2

Low/high

(c) Niacin

Class 3

Class 3

High/low

7

Beta-Adrenergic

Blocking Agents

(a) Atenolol

Class 3

Class 3

High/low

(b) Bisoprolol

Class 1

Class 3

High/low

(c) Metoprolol

Class 1

Class 1

High/high

(d) Propranolol

Class 1

Class 1

High/high

8

Calcium Channel Antagonists

(a) Amlodipine

Class 1

Class 1

High/high

(b) Benidipine

Class 2

Class 2

Low/high

(c) Cilnidipine

–

–

—/high

(d) Diltiazen

Class 1

Class 1

High/high

(e) Lercsnidipine

–

–

––/high

(f) Manidipine

Class 2

Low/high

(g) Nicardipine

Class 1

Class 1

High/high

(h) Nifedipine

Class 2

Class 2

Low/high

(i) Nilvadipine

Class 2

–

Low/high

(j) Verapamil

Class 2

Class 2

Low/high

9

Cardiovascular Agents

Class 3

Class 3

High/low

(a) Digoxin

(b) Methyldopa

Class 3

Class 3

High/low

10

Diuretics

(a) Acetazolamide

Class 4

Class 4

Low/low

(b) Amiloride

Class 3

Class 3

High/low

(c) Furosemide

Class 4

Class 4

Low/low

(d) Hydrochlorothiazide

Class 4

Class 4

Low/low

(e)Indapamide

Class 1

Class 1

High/high

(e) Spironolactone

Class 2

Class 2

Low/high

11

HMG-CoA Reductase Inhibitors

Class 2

Class 2

Low/high

(a) Atorvastatin

(b) Fluvastatin

Class 1

Class1

High/high

(c) Lovastatin

Class 2

Class 2

Low/high

(d) Parvastatin

Class 1

Class 3

High/low

(e) Simvastatin

Class 2

Class 2

Low/high

12

Vasodilators

(a) Beraprost

Class 1

Class 1

High/high

(b) Hydralazine

Class 3

Class 3

High/low

(c) Isosorbide dinitrate

Class 3

Class 3

High/low

(d) Limaprost

Class 1

Class1

High/high

(e) Nicorandil

Class 3

–

High/low

(f) Nitroglycerin

Class 1

Class 3

High/low

(g) Trimetazidine

Class 3

Class 3

High/low