Table 6 Pharmacokinetic parameters of piperine in human body
Route of administration | Dose (mg) | Cmax (ng/mL) | Tmax (h) | AUC0−∞ (μg h/mL) | t1/2 (h) | References |
|---|---|---|---|---|---|---|
Oral | 24 | 3.77 ± 1.63 | 2.15 ± 1.21 | 58.41 ± 23.50 | 8.74 ± 8.95 | Itharat et al. [189] |
Oral | 20 | 290.00 ± 42.47 595.4 ± 108.6 | – – | 59.32 ± 10.82 15.79 ± 50.50 | 13.26 ± 1.91 15.82 ± 4.95 | Wen-xing [190] |
Oral | 20 | 290 ± 40 | 3.50 ± 1.78 | 5.93 ± 1.08 | 13.3 ± 1.9 | Ren and Zuo [191] |