Table 3 Examples of therapeutic plants under plant tissue culture trials with anticancer activity
From: Phyto-factories of anti-cancer compounds: a tissue culture perspective
Plant | Explant used | Culture technique | Bioactive agent | Media | Cancer | References |
|---|---|---|---|---|---|---|
Parwal (Andrographis lineate) | Mature leaf explant | Callus culture | 7-O-Methylwogonin (MW) and Echioidinin (ED) | MS with 1.0 mgL–1 IAA | Leukemic cell line, CEM | [55] |
Periwinkle (Catharanthus roseus) | Root | Hairy root culture | Vincristine | MS | Cancer | [56] |
Turnip (Brassica rapa) | Seeds | Hairy root culture | Glucosinolates | DMEM medium supplemented with 10% FBS | Colon HT-29 (human colorectal adenocarcinoma) and oestrogen-dependent breast MCF-7 (human breast adenocarcinoma) cell lines | [78] |
Plume poppy (Macleaya cordata) | Leaves and stems | Hairy root culture | Sanguinarine | Hormone-free MS media, 200 mg L−1 timentin | Colon cancer | [75] |
Hedgehog coneflower (Echinacea purpurea) | Leaf | Callus culture | Flavanoids | MS,2,4-D, NAA, ZnO nanoparticles | MCF-10 cells and peripheral blood monolayer cells | [76] |
Golden flax (Linum flavum) | Root | Hairy Root Cultures | Aryltetralin lignin | Gamborg B5 medium with methyl jasmonate, and ferulic acid | Cancer | [82] |
Dessert bush (Aerva javanica) | Leaf and leaf derived callus | Callus culture | – | MS with IAA and NAA | MCF-7 breast cancer cell line | [83] |
Tea (Camellia sinensis) | Leaf | Hairy root cultre | Polyphenols | 1% MS (Murashige and Skoog) and water | – | [77] |
Phyllanthus amarus | Shoot | Hairy root culture | Reactive Oxygen Species | MS with 2.0 mg L–1 BAP | MCF-7 cell | [2] |