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Table 3 Demographic and biochemical characteristics of control and ovarian cancer patients

From: Gene polymorphisms of Interleukin 6 (−174 G/C) and transforming growth factor β-1(+915 G/C) in ovarian cancer patients

Laboratory investigations

Control (N = 48) (mean ± SD)

Ovarian cancer (N = 48) (mean ± SD)

P value

Correlation with OC

Age (years)

45.25 ± 15.31

50.59 ± 11.93

NS

r = 0.239*

CA125 (U/ml)

12.92 ± 7.29

176.30 ± 244.91

P < 0.01**

r = 0.430***

TLC (1000/mm3)

7.50 ± 1.83

6.18 ± 2.20

P < 0.01**

r =  − 0 .311**

HB (g/dl)

11.71 ± 1.36

11.25 ± 2.06

NS

r =  − 0.168

PLT (1000/mm3)

269.52 ± 68.22

276.91 ± 142.88

NS

r = 0.033

AST (IU/L)

20.77 ± 6.12

32.50 ± 18.77

P < 0.001***

r = 0.391***

ALT (IU/L)

18.95 ± 5.49

34.95 ± 18.61

P < 0.001***

r = 0.507***

ALB (g/dL)

4.25 ± 0.42

3.16 ± 0.56

P < 0.001**

r =  − 0.737***

T.Bili (mg/dl)

0.65 ± 0.17

0.55 ± 0.38

NS

r =  − 0.157***

Cr. (mg/dl)

0.88 ± 0.1

0.91 ± 0.3

NS

r = 0.066

BUN (mg/dl)

9.60 ± 2.04

11.35 ± 3.64

P < 0.01**

r = 0.286**

  1. PLT Platelet, AST Aspartate aminotransferase, ALT Alanine aminotransferase, ALB Albumin, TLC Total leucocytic count, Cr Creatinine, BUN Blood urea nitrogen, CA125 Cancer antigen 125, NS not significant, HB Hemoglobin, T.Bili. Total bilirubin
  2. *P < 0.05; **P < 0.01; ***P < 0.001