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Beni-Suef University Journal of Basic and Applied Sciences

Table 1 Showed the effect of the treatment with Bisphenol A itself or together with costus root extract on the weight of body and testis

From: Costus root extract improves testicular toxicity of Bisphenol A in adult male albino rats: histopathological, ultrastructural and biochemical studies

 

First (control) group

Second group costus root extract seeds

Third group Bisphenol A

Fourth group Bisphenol A with costus root extract

Body weight

287 ± 2.4

264 ± 1.9

183 ± 1.8*

265 ± 3.1**

Testis weight

2.72 ± 0.2

2.31 ± 0.3

1.89 ± 0.6*

2.9 ± 0.2**

  1. The first group received distilled water daily for eight weeks
  2. The second group was treated with Costus root extract at a dose (0.4 mg/kg) daily
  3. The third group was treated with 10 mg/kg of Bisphenol A (BPA) (body weight /day) dissolved in 5 ml/kilogram of oil of olive
  4. The fourth group received 10 mg/kg of Bisphenol A (bwt/day) Costus root extract at a dose (0.4 mg/kg) daily for eight weeks was given by gastric gavage daily
  5. *p < 0.05 (significant difference in comparison with control group and second groups)
  6. **p < 0.05 (significant difference in comparison with third group)
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