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Table 2 Effect of the administration of Bisphenol A itself or together with costus root extract on antioxidant enzymes of testis CAT, GPx, SOD, GSH, MDA, and NO

From: Costus root extract improves testicular toxicity of Bisphenol A in adult male albino rats: histopathological, ultrastructural and biochemical studies

 

First (control) group

Second group costus root extract

Third group Bisphenol A

Fourth group Bisphenol A with costus root extract

CAT

08.01 ± 0.31

09.03 ± 0.83

03.8 ± 0.05*

07.9 ± 0.02**

SOD

08.03 ± 0.21

08.9 ± 0.11

04.5 ± 0.02*

07.89 ± 0.23**

GPx

71.18 ± 0.48

64.08 ± 0.03

52.81 ± 0.5*

61.91 ± 0.4**

GSH

23.03 ± 0.14

22.01 ± 0.01

10.19 ± 0.2*

022.9 ± 0.1**

MDA

14. 03 ± 0.39

13.9 ± 0.12

017.01 ± 0.92*

12.1 ± 0.01**

NO

99.09 ± 0.98

92.34 ± 0.43

110.2 ± 0.13*

94.01 ± 0.02**

  1. The first group received distilled water daily for eight weeks
  2. The second group was treated with Costus root extract at a dose (0.4 mg/kg) daily
  3. The third group was treated with 10 mg/kg of Bisphenol A (BPA) (body weight /day) dissolved in 5 ml/kilogram of oil of olive
  4. The fourth group received 10 mg/kg of Bisphenol A (bwt/day) Costus root extract at a dose (0.4 mg/kg) daily for eight weeks was given by gastric gavage daily
  5. *p < 0.05 (significant difference in comparison with control group and second groups)
  6. **p < 0.05 (significant difference in comparison with third group)