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Table 10 Drug-likeness and medicinal chemistry of compounds 13 and 21

From: Computational and pharmacokinetics studies of 1,3-dimethylbenzimidazolinone analogues of new proposed agent against Alzheimer's disease

 

Compound 13

Compound 21

Lipinski violations

0

0

Ghose violations

0

0

Veber violations

0

0

Egan violations

0

0

Muegge violations

0

0

Lead-likeness violations

1

2

PAINS alerts

0

0

Synthetic accessibility

3.30

2.85