Clinicophysiological and hematobiochemical effect of dexmedetomidine or diazepam with ketamine and propofol in total intravenous anesthesia in goats

Ragab, G.; Hassan, S. E.; Fathi, M. Z.; Hagag, U.

doi:10.1186/s43088-022-00232-0

Beni-Suef University Journal of Basic and Applied Sciences

Table 3 Mean ± standard deviation (SD) of hematobiochemical parameters at different time intervals

From: Clinicophysiological and hematobiochemical effect of dexmedetomidine or diazepam with ketamine and propofol in total intravenous anesthesia in goats

Parameter		Time (min)
Parameter		Baseline	15	30	60	120	240
PH	Group Ι	7.42^bc ± 0.01	7.37^e ± 0.01	7.28^g ± 0.01	7.41^bc ± 0.01	7.47^a ± 0.01	7.40^cd ± 0.01
PH	Group ΙΙ	7.42^bc ± 0.01	7.33^f ± 0.01	7.34^f ± 0.01	7.40^cd ± 0.01	7.38^de ± 0.01	7.43^b ± 0.03
PCO₂ (mmHg)	Group Ι	42.80^bc ± 3.15	49.77^abc ± 3.60	54.91^a ± 4.04	44.30^bc ± 3.25	34.90^d ± 2.55	44.10^bc ± 3.25
PCO₂ (mmHg)	Group ΙΙ	42.0^c ± 4.39	45.73^bc ± 4.79	50.57^ab ± 5.29	44.13^bc ± 4.59	43.20^bc ± 4.49	42.80^bc ± 3.93
PO₂ (mmHg)	Group Ι	34.67^de ± 3.21	51.67^b ± 4.93	38.88^cde ± 3.41	62.67^a ± 5.85	31.0^e ± 2.64	47.49^bc ± 4.41
PO₂ (mmHg)	Group ΙΙ	39.67^cde ± 5.51	43.97^bcd ± 6.11	47.17^bc ± 6.55	38.60^cde ± 5.39	48.67^bc ± 6.75	53.67^ab ± 7.23
HCO₃ (mmol/L)	Group Ι	26.03^ab ± 1.05	29.27^a ± 1.20	26.74^ab ± 1.08	28.73^a ± 1.15	27.17^ab ± 2.15	28.72^a ± 1.16
HCO₃ (mmol/L)	Group ΙΙ	25.0^b ± 2.10	26.50^ab ± 2.20	24.93^b ± 2.10	25.10^b ± 2.10	28.70^a ± 2.40	27.0^ab ± 2.0
SO₂ (%)	Group Ι	66.46^cde ± 9.22	81.80^abc ± 11.34	58.38^e ± 8.11	87.73^a ± 12.15	64.86^de ± 8.95	76.04^abcd ± 10.5
SO₂ (%)	Group ΙΙ	75.16^abcd ± 6.02	85.60^ab ± 6.87	69.93^bcde ± 5.61	63.33^de ± 5.08	87.07^a ± 6.98	85.93^a ± 6.98
Glucose (mg/dL)	Group Ι	89.33^c ± 17.09	176.3^abc ± 33.6	234.3^a ± 39.11	195.0^ab ± 37.40	137.0^ab ± 26.1	87.0^c ± 15.72
Glucose (mg/dL)	Group ΙΙ	113.7^bc ± 57.01	118.3^bc ± 59.5	152.3^abc ± 76.5	148.3^abc ± 74.5	109.3^bc ± 55.0	88.7^c ± 44.95
BUN (mg/dL)	Group Ι	34.0^b ± 2.64	35.0^b ± 2.64	39.0^ab ± 3.60	40.0^ab ± 3.60	33.0^b ± 2.64	40.0^ab ± 3.0
BUN (mg/dL)	Group ΙΙ	40.6^ab ± 15.04	44.2^ab ± 16.34	59.0^ab ± 21.70	55.3^ab ± 20.56	66.7^a ± 24.58	59.0^ab ± 21.70
Creatinine (mg/dL)	Group Ι	1.17^a ± 0.56	1.03^a ± 0.35	0.83^a ± 0.40	0.93^a ± 0.42	1.03^a ± 0.51	1.30^a ± 0.62
Creatinine (mg/dL)	Group ΙΙ	0.83^a ± 0.15	0.83^a ± 0.15	0.83^a ± 0.15	0.83^a ± 0.15	0.93^a ± 0.15	0.73^a ± 0.15

Within each comparison, means with different superscripts are statistically significant at a 0.05 level of significance (P < 0.05). Small letters represent the interaction effects of both treatment and time. Capital letters represent the overall significance (main effect of treatment and main effect of time)

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