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Table 4 List of used codons based on frequency in ORF4 of hepatitis E viruses

From: Analysis of codon usage patterns in open reading frame 4 of hepatitis E viruses

Host organism

Codon (aa)

Frequency

Codon (aa)

Frequency

Human

Most frequent

CCC (P)

11

GCC(A)

5

 

CCG(P)

10

CCA(P)

5

 

UUG(L)

8

UCA(S)

5

 

UGC (C)

7

CAG(Q)

5

 

UCG(S)

5.6

GGC(G)

5

Least frequent

CUU(L)

1

AAC(N)

1

 

CUC(L)

1

AAG(K)

1

 

GUC(V)

1

GAU(D)

1

 

GUA(V)

1

CGU(R)

1

 

ACU(T)

1

AGA(R)

1

 

GCA(A)

1

GGU(G)

1

 

UAU(Y)

1

GGA(G)

1

 

CAA(Q)

1

  

Not used

UUU(F)

0

AAU(N)

0

 

AUA(I)

0

AAA(K)

0

 

UCU(S)

0

GAC(D)

0

 

UAC(Y)

0

GAA(E)

0

 

CAU(H)

0

UGU(C)

0

 

CAC(H)

0

AAU(N)

0

Rat

Most frequent

CUG(L)

7.6

AGC(S)

6.1

 

UUG(L)

7.4

UUC(F)

5.7

 

CGC(R)

7.1

CUC(L)

5.6

 

CUA(L)

7

CGG(R)

5.4

 

GCC(A)

6.7

UGC(C)

5

 

AGG(R)

6.6

GGC(G)

5

Least frequent

CAU(H)

0.1

CGA(R)

0.7

 

AGA(R)

0.1

CAA(Q)

0.7

 

GAC(D)

0.1

ACU(T)

1

 

GAA(E)

0.1

UAU(Y)

1

 

GUC(V)

0.3

CGU(R)

1

 

CAC(H)

0.6

  

Unused

AAA(K)

0

GGA(G)

0

 

AGU(S)

0

  

Ferret

Most frequent

UUG(L)

8.5

UCU(S)

5.7

 

CGC(R)

8.5

CUA(L)

5.3

 

CAG(Q)

8.3

UUU(F)

5.2

 

AGG(R)

6.8

CUG(L)

5

 

GCC(A)

5.8

CCC(P)

5

Least frequent

AAG(K)

0.2

GUA(V)

1

 

CAU(H)

0.2

ACU(T)

1

 

CGA(R)

0.2

UAU(Y)

1

 

AAC(N)

0.4

GAA(E)

1

 

UUA(L)

1

AGA(R)

1

Unused codons

AAU(N)

0

GAC(D)

0

 

AAA(K)

0

AGU(S)

0

  1. The table lists codons, the amino acid (aa) encoded by the codon (in parentheses), and frequency of use (as a percentage). Codons are listed from most to least frequent. The space in the table separates the most frequently used, least frequently used and the unused codons for each host