In situ green analytical methods for the rapid and sensitive determination of a newly launched orphan anticancer drug; Tigecycline in infusion bags: comparative study

Beni-Suef University Journal of Basic and Applied Sciences

Table 5 Application of the proposed methods for determination of TIG in intravenous infusion solution for five determinations

Pharmaceutical preparation	Recovery %^a ± % RSD^b
	CZE method	Spectrophotometric methods			Reported HPLC method [3]
	CZE method	Method I	Method II	Method III	Reported HPLC method [3]
Tygacil® vials	100.89 ± 0.52	100.69 ± 0.73	100.67 ± 0.54	100.50 ± 0.54	101.01 ± 0.46
t^c	0.38	0.83	1.08	1.60
F^d	1.24	2.43	1.32	1.32