Table 1 Statistical analysis of results of comparison of LAMP with PCR and blood smear examination using MedCalc's Diagnostic test evaluation calculator
TEST | PCR | Blood smear | ||||
|---|---|---|---|---|---|---|
LAMP | Positive | Negative | Total | Positive | Negative | Total |
Positive | 23 | 4 | 27 | 16 | 11 | 27 |
Negative | 0 | 73 | 73 | 0 | 73 | 73 |
Total | 23 | 77 | 100 | 16 | 84 | 100 |
Statistics | Value | 95% confidence interval | Value | 95% confidence interval |
|---|---|---|---|---|
Sensitivity | 100.00% | 85.18–100.00% | 100.00% | 79.41–100.00% |
Specificity | 94.81% | 87.23–98.57% | 86.90% | 77.78–93.28% |
Positive likelihood ratio | 19.25 | 7.41–49.98 | 7.64 | 4.40–13.25 |
Negative likelihood ratio | 0.00 | Â | 0.00 | Â |
Disease prevalence | 23.00% | 215.17–32.49% | 16.00% | 9.43–24.68% |
Positive predictive value | 85.19% | 68.89–93.72% | 59.26% | 45.61–71.62% |
Negative predictive value | 100.00% | Â | 100.00% | Â |
Accuracy | 96.00% | 90.07–98.90% | 89.00% | 81.17–94.38% |
Kappa | 0.894 | 0.680 | ||
S.E. of kappa | 0.052 | 0.086 | ||
95% confidence interval | 0.792 to 0.995 | 0.511 to 0.849 | ||