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Table 4 Relation between IGF rs6214 genotypes and different parameters in colorectal Cancer group (n = 80)

From: Linking insulin like growth factor-1 (IGF-1) rs6214 gene polymorphism and its serum level with risk of colorectal cancer

 

IGF rs6214

Test of Sig

p

CC (n = 12)

CT (n = 28)

TT (n = 40)

Sex

 Male

7 (58.3%)

17 (60.7%)

23 (57.5%)

χ2 = 0.071

0.965

 Female

5 (41.7%)

11 (39.3%)

17 (42.5%)

  

Age (years)

11.6 ± 44.9

11.8 ± 46

12.6 ± 52.4

F = 3.115

0.050

ALT

4.6 ± 33.3

4.8 ± 32.6

4.3 ± 33.7

F = 0.443

0.643

AST

4.6 ± 32.1

4.2 ± 31.7

4.6 ± 30.9

F = 0.450

0.639

UREA

10.1 ± 30.2

10.2 ± 28.9

9.3 ± 28.7

H = 0.314

0.855

Creatinine

0.2 ± 1

0.2 ± 1

0.3 ± 1

F = 0.285

0.753

CA19-9 (U/ml)

6.9 ± 8.5

6.4 ± 10.5

72.9 ± 122.7

H = 34.668*

< 0.001*

CEA (mg/dl)

1.6 ± 31.1

2.9 ± 33.5

23.4 ± 55.9

H = 50.170*

< 0.001*

Serum IGF-1 (ng/ml)

1.9 ± 122.2

4.9 ± 131.6

32.6 ± 175.3

F = 40.227*

< 0.001*

  1. χ2: Chi square test, F: F for ANOVA test, H: for Kruskal Wallis test