Table 5 Genes belonging to each cluster with respective MCODE scores and clustering coefficients: clusters were ranked based on the MCODE scores which implied that C1 had the highest total density around each node in the cluster

C1

36

1

36

630

CUL5, SOCS1, KLHL2, RNF138, TRIM21, CBLB, UBE2Q2, PJA2, UBE2L6, PJA1, HERC5, ASB8, RBCK1, UBE2G2, WWP1, CDC26, RNF213, TRIP12, FBXL3, FBXO9, MEX3C, ANAPC1, UBE4A, FBXO31, KLHL3, ANAPC13, FBXL5, UBE2E1, KCTD6, FBXO7, SOCS3, UBE2K, FBXO6, UBE2O, KBTBD7, UBA6

C2

32

1

32

496

CCR2, PNOC, FPR1, GNG7, C3AR1, FPR2, S1PR5, CXCL10, CXCR6, PTGDR2, GNAI3, GPR18, CCR3, LPAR5, ADCY3, GPR183, HCAR3, HCAR2, CCL4L1, P2RY14, CCR1, P2RY13, PPBP, CCR7, CXCL16, CXCR5, GNB4, CXCR1, HEBP1, GNG11, CXCR3, S1PR1

C3

28.414

0.959

30

412

C18orf32, RPL7, RPS3, RPS23, RPS15A, RPS8, RPL13A, RPL23, RPS28, RPS5, SPCS3, RPN2, EIF3A, RPL13, RPS2, RPL4, RPL22, MRPL15, RPLP0, RPL36, RPL3, RPL21, RPS4X, RPL26, RPL9, RPSA, RPL5, GSPT2, SRP9, SRP72

C4

22.366

0.944

72

794

CEACAM1, LILRB2, P2RX1, PGLYRP1, BST1, CYFIP1, TCN1, CLEC4D, BPI, OLR1, FCER1G, QPCT, ITGAM, MCEMP1, HLA-F, GPR97, CAMP, PLAUR, SLC2A3, CLEC12A, OSCAR, ORM1, CEACAM3, CYBB, GBP2, ATP8B4, CLEC5A, ITGAX, LAMTOR3, ARG1, HLA-G, VCL, HLA-C, KPNB1, CTSD, DEGS1, OLFM4, RSAD2, MX1, SLC11A1, IRF7, ATP6AP2, RAP2C, CD36, OASL, LRG1, NBEAL2, XAF1, MGAM, IFI6, HP, HPSE, IFIT1, IFIT3, IFIT2, STAT2, ELANE, FOLR3, IFITM1, IFI35, OAS3, IRF1, IRF8, LCN2, RNASEL, CEACAM8, ISG15, GPR84, OAS1, DEFA4, IFITM3, TOM1

C5

11.556

0.861

55

312

METTL7A, WSB2, MMP9, CISH, PICALM, PACSIN1, FCGR1A, CDA, CREG1, STAT1, IL-7R, RTP4, DCUN1D1, TRIM25, GBP5, CD44, CTSA, SCARB2, VAMP7, GCA, LDLRAP1, FTH1, REPS2, SYNJ1, GBP1, SDCBP, BIN1, MT2A, FCHO1, GRN, CD3D, EIF2AK2, ARPC5, TRIM22, IFI30, DNM3, GNS, IFIH1, RNASE2, FCGR1B, CD3G, IFI44, NHLRC3, IFI44L, ACTR3, NPC2, RAB5A, HEBP2, AGFG1, MPO, TNFAIP6, GBP4, PLAC8, EGF, COMMD8

C6

10.889

0.905

19

98

DHX15, HNRNPC, CSTF3, CSNK1E, LSM4, SMNDC1, TRA2B, HNRNPL, WBSCR22, PAPOLA, SNRNP27, DHX9, SNRNP40, SNRPN, PPWD1, BMS1, UTP3, HNRNPA1, RIOK3