Table 10 Post-compression parameters
From: Development and characterization of solid dispersion-based orodispersible tablets of cilnidipine
Formulations | Weight variation (mg) | Thickness (mm) | Hardness (Newton) | Friability (%) | Drug content (%) | Disintegration time (s) |
|---|---|---|---|---|---|---|
F1 | 0.19 ± 0.01 | 1.3 ± 0.1 | 33.0 ± 1.73 | 0.38 ± 0.03 | 92.1 ± 0.78 | 42.0 ± 2.16 |
F2 | 0.20 ± 0.01 | 1.2 ± 0.1 | 32.6 ± 1.15 | 0.24 ± 0.06 | 93.6 ± 0.16 | 42.3 ± 2.05 |
F3 | 0.20 ± 0 | 1.2 ± 0.1 | 29.6 ± 1.52 | 0.38 ± 0.10 | 92.4 ± 0.32 | 42.6 ± 1.24 |
F4 | 0.20 ± 0.01 | 1.2 ± 0.1 | 33.6 ± 0.58 | 0.49 ± 0.13 | 91.4 ± 0.36 | 40.3 ± 0.94 |
F5 | 0.20 ± 0.01 | 1.1 ± 0.1 | 31.3 ± 1.15 | 0.38 ± 0.17 | 93.2 ± 0.20 | 32.0 ± 1.63 |
F6 | 0.19 ± 0.007 | 1.3 ± 0 | 32.3 ± 0.57 | 0.35 ± 0.21 | 92.4 ± 0.09 | 40.3 ± 1.24 |
F7 | 0.35 ± 0.01 | 1.1 ± 0.1 | 30.6 ± 0.58 | 0.35 ± 0.03 | 92.7 ± 0.16 | 40.3 ± 0.47 |
F8 | 0.20 ± 0.01 | 1.3 ± 0.1 | 33.0 ± 1.73 | 0.38 ± 0.10 | 92.3 ± 0.12 | 42.6 ± 1.24 |
F9 | 0.19 ± 0.007 | 1.2 ± 0 | 31.3 ± 0.57 | 0.27 ± 0.03 | 92.1 ± 0.14 | 36.3 ± 1.24 |
F10 | 0.20 ± 0 | 1.2 ± 0.1 | 31.0 ± 1.0 | 0.35 ± 0.14 | 93.4 ± 0.32 | 32.6 ± 0.47 |
F11 | 0.19 ± 0.01 | 1.3 ± 0 | 32.0 ± 0 | 0.33 ± 0.13 | 93.3 ± 0.12 | 26.6 ± 1.24 |
F12 | 0.19 ± 0.01 | 1.1 ± 0.1 | 32.3 ± 0.57 | 0.27 ± 0.08 | 93.4 ± 0.09 | 32.0 ± 0 |