Table 3 Phase solubility study of drug with aqueous solution of carrier
From: Development and characterization of solid dispersion-based orodispersible tablets of cilnidipine
Carrier | 5% (mg/ml) | Inference | 10% (mg/ml) | Inference | 15% (mg/ml) | Inference |
|---|---|---|---|---|---|---|
PVP | 0.3805 | Very slightly soluble | 0.6722 | Very slightly soluble | 0.9976 | Very slightly soluble |
PEG 6000 | 0.0463 | Practically insoluble | 0.0876 | Practically insoluble | 0.1076 | Very slightly soluble |
Poloxamer 188 | 0.0638 | Practically insoluble | 0.1277 | Very slightly soluble | 0.2491 | Very slightly soluble |