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Beni-Suef University Journal of Basic and Applied Sciences
Fig. 12 | Beni-Suef University Journal of Basic and Applied Sciences

Fig. 12

From: Alpha-lipoic acid-role in improving both reserpine toxicity and paroxetine treatment in the cerebral cortex of albino rats; histological, ultrastructural, immunohistohemical and biochemical studies

Fig. 12

Photomicrographs obtained from sections of cerebral cortex a: of control rat showing caspase-3 expression in the cytoplasm of few granular and pyramidal cells (arrows). b: obtained from ALA-treated animal showing normal caspase-3 expression. c: section of reserpine-treated rat showing an increase in number of cells with positive caspase-3 expression (arrows). d: section obtained from animal treated with reserpine and paroxetine showing positive caspase-3 expression in the cytoplasm of considerable number of cells (arrows). e: section obtained from depressed animal treated with ALA and paroxetine showing nearly normal caspase-3 expression appeared in few pyramidal and granular cells (arrows)

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