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Beni-Suef University Journal of Basic and Applied Sciences

Table 1 Percentage area of PCNA and caspase-3 expressions in the cerebral cortex of rats in the different experimental groups

From: Alpha-lipoic acid-role in improving both reserpine toxicity and paroxetine treatment in the cerebral cortex of albino rats; histological, ultrastructural, immunohistohemical and biochemical studies

Groups

Parameter

The percentage areas of PCNA expression

(Mean ± SD)

The percentage areas of caspase-3 expression

(Mean ± SD)

Control

2.15 ± 0.46

1.63 ± 0.03

ALA

2.02 ± 0.09

1.71 ± 0.26

Reserpine

1.08 ± 0.91**

13.50 ± 1.78**

Reserpine + paroxetine

2.99 ± 0.94*a

14.26 ± 2.43**

Reserpine + paroxetine + ALA

2.10 ± 0.77a

4.24 ± 0.62**a

  1. n = 8 animals for each group
  2. (*) P ≤ 0.05 and (**) P ≤ 0.0001 significant comparing with control group
  3. aP ≤ 0.0001 significant comparing with reserpine group
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