Table 2 Self-emulsification time, appearance, and phase separation of vorinostat-loaded SMEDDS
Formulation code | Self-emulsification time (min)* | Appearance | Phase separation for 24Â h# |
|---|---|---|---|
F1 | 1.95 ± 0.26 | Bluish white | NPS |
F2 | 1.38 ± 0.12 | Bluish white | NPS |
F3 | 2.58 ± 0.51 | Bluish white | NPS |
F4 | 2.27 ± 0.02 | Bluish white | NPS |
F5 | – | Large oil droplets | NPS |
F6 | 1.08 ± 0.01 | Bluish white | NPS |
F7 | 1.47 ± 0.05 | Clear and transparent | NPS |
F8 | 1.18 ± 0.01 | Clear and transparent | NPS |
F9 | – | Large oil droplets | NPS |
F10 | – | Large oil droplets | NPS |
F11 | 1.30 ± 0.05 | Clear and transparent | NPS |
F12 | 0.88 ± 0.06 (53 ± 4 s) | Clear and transparent | NPS |