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Table 3 The pH of vorinostat-loaded SMEDDS in different media

From: Improved oral bioavailability of poorly water-soluble vorinostat by self-microemulsifying drug delivery system

Media pH SMEDDS in media (1:1000)
F7 F8 F11 F12
UPW 7.7 5.37 ± 0.050 5.21 ± 0.049 5.40 ± 0.034 5.35 ± 0.035
0.1 M HCl 1.15 1.20 ± 0.105 1.22 ± 0.030 1.21 ± 0.030 1.21 ± 0.061
PB 6.8 6.70 ± 0.120 6.85 ± 0.122 6.78 ± 0.085 6.80 ± 0.121
  1. Each value represents the mean ± SD (n = 3)
  2. UPW ultra-pure water, PB phosphate buffer, HCl hydrochloric acid