Fig. 4

A Cartoon and B surface representation of the docked hsCENP-HIKM complex. The hsCENP-I is colored in two shades of yellow in order to distinguish the N-terminal (pale yellow) from the C-terminal. The binding of the hsCENP-M to the C-terminal of hsCENP-I shows great resemblance with the previously described binding of Ran to importin-β. The hsCENP-H, hsCENP-K and hsCENP-M are colored in blue, green and red, respectively