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Table 4 Effect of aqueous extract of B. sapida leaves on selected marker enzymes of P. berghei-infected female albino mice

From: Antiplasmodial evaluation of aqueous extract of Blighia sapida K.D. Koenig leaves in Plasmodium berghei (NK65)-infected mice

Groups

ALT (U/L)

AST(U/L)

LDH (× 103 U/L)

ALP(U/L)

Not infected + distilled water

58.81 ± 0.27b

44.33 ± 1.69a

0.59 ± 0.02a

96.91 ± 5.75a

Infected + distilled water

66.32 ± 1.14c,d

81.17 ± 2.52e

2.22 ± 4.34b,c

200.10 ± 36.38b

Infected + 5 mg/Kg/day CQ

66.88 ± 0.47d

52.33 ± 1.17b

1.54 ± 0.40a,b

102.58 ± 0.80a

Infected + 125 mg/Kg/day of extract

42.75 ± 1.08a

59.33 ± 1.64c

3.00 ± 0.36c

86.71 ± 13.50a

Infected + 250 mg/Kg/day of extract

59.94 ± 1.57b

67.00 ± 1.44d

3.00 ± 0.78c

82.19 ± 12.57a

Infected + 500 mg/Kg/day of extract

62.19 ± 2.66b,c

72.33 ± 2.57d

3.35 ± 0.02d

71.61 ± 4.16a

  1. Values are mean  ± S.E.M (n = 8)
  2. CQ chloroquine; ALT alanine aminotransferase; AST aspartate aminotransferase; LDH lactate dehydrogenase; ALP alkaline phosphatase
  3. Values with different alphabets superscripts in the same column are significantly different at P < 0.05