Table 1 Formulation composition of mucoadhesive minitablets of cefuroxime axetil
Formulation code | Cefuroxime axetil (mg) | Chitosan (mg) | HPMC K100M (mg) | Sodium CMC (mg) | Lactose (mg) | Talc (mg) | Total weight (mg) |
|---|---|---|---|---|---|---|---|
F1 | 10 | 2 | – | – | 8 | 1 | 21 |
F2 | 10 | 4 | – | – | 6 | 1 | 21 |
F3 | 10 | 6 | – | – | 4 | 1 | 21 |
F4 | 10 | 8 | – | – | 2 | 1 | 21 |
F5 | 10 | 10 | – | – | 0 | 1 | 21 |
F6 | 10 | – | 2 | – | 8 | 1 | 21 |
F7 | 10 | – | 4 | – | 6 | 1 | 21 |
F8 | 10 | – | 6 | – | 4 | 1 | 21 |
F9 | 10 | – | 8 | – | 2 | 1 | 21 |
F10 | 10 | – | 10 | – | 0 | 1 | 21 |
F11 | 10 | – | – | 2 | 8 | 1 | 21 |
F12 | 10 | – | – | 4 | 6 | 1 | 21 |
F13 | 10 | – | – | 6 | 4 | 1 | 21 |
F14 | 10 | – | – | 8 | 2 | 1 | 21 |
F15 | 10 | – | – | 10 | 0 | 1 | 21 |