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Table 3 Point prediction and confirmation data of CA through ANOVA

From: Formulation development, optimization and characterization of mucoadhesive minitablets of cefuroxime axetil: in vitro, ex vivo and in vivo pharmacokinetic evaluation

Run 7 response

Predicted mean

Predicted median

Observed

Std Dev

SE Mean

95% CI low for mean

95% CI high for mean

95% TI low for 99% Pop

95% TI high for 99% Pop

% Friability (R1)

0.185

0.185

0.163

0.0057735

0.005

0.172147

0.197853

0.143854

0.226146

% Drug content (R2)

95.0125

95.0125

99.18

0.514296

0.445393

93.8676

96.1574

91.3473

98.6777

% Mucoadhesive strength (R3)

6.81013

6.81013

6.489

0.445406

0.385733

5.81857

7.80168

3.63587

9.98438

  1. Two-sided, Confidence = 95%, Population = 99%; R: Response