Table 7 Pharmacokinetic parameters estimation for the aqueous suspension of CA and mucoadhesive minitablets
PK parameters | Aqueous suspension of CA* | Mucoadhesive minitablets* |
|---|---|---|
Cmax (ng/mL) | 2548.295 ± 354.82 | 8795.32 ± 423.58 |
Tmax (h) | 4 ± 0.02 | 4 ± 0.03 |
AUC (ng h)/mL | 19690.11 ± 125.56 | 73857.32 ± 314.15 |
AUMC (ng/h2)/mL | 99178.5 ± 269.47 | 592716.1 ± 358.4 |
MRT (h) | 5.03 ± 0.025 | 8.025151 ± 0.031 |