Cell line | Time | CONC (ppm) | TAEO | FAEO | P-value | ||||
---|---|---|---|---|---|---|---|---|---|
Viability % | IC50 | Viability % | IC50 | ||||||
Mean | SD | Mean | SD | ||||||
MCF-7 | 24 h | Control | 100.1 | 0.89 | 228.6 ± 21.53 | 100.96 | 5.46 | > 400 | 0.72 |
100 | 85 | 7.58 | 81.20 | 2.52 | 0.44 | ||||
200 | 61.33 | 6.50 | 71.89 | 4.58 | 0.08 | ||||
400 | 7.19 | 0.52 | 71.31 | 5.56 | < 0.0001 | ||||
48 h | Control | 99.6 | 0.89 | 209.8 ± 20 | 100.01 | 2.39 | > 400 | 0.72 | |
100 | 89.57 | 2.91 | 81.98 | 1.14 | 0.008 | ||||
200 | 50.5 | 8.42 | 70.99 | 3.32 | 0.03 | ||||
400 | 5.21 | 0.70 | 59.95 | 3.47 | < 0.0001 | ||||
72 h | Control | 100.16 | 0.61 | 192.5 ± 42.57 | 100.04 | 2.60 | > 400 | 0.93 | |
100 | 77.25 | 12.73 | 80.72 | 6.00 | 0.74 | ||||
200 | 31.57 | 4.85 | 71.33 | 1.88 | 0.008 | ||||
400 | 2.33 | 0.57 | 55.84 | 0.08 | < 0.0001 | ||||
MDA-MB-468 | 24 h | Control | 99.83 | 0.76 | 336.6 ± 20.84 | 100.47 | 1.75 | > 400 | 0.57 |
100 | 99.58 | 1.01 | 90.94 | 5.94 | 0.03 | ||||
200 | 83.32 | 2.55 | 86.50 | 5.73 | 0.40 | ||||
400 | 41.52 | 3.31 | 80.93 | 5.95 | < 0.0001 | ||||
48 h | Control | 100.06 | 0.40 | 334.1 ± 36.96 | 100.32 | 1.27 | > 400 | 0.75 | |
100 | 95.61 | 5.86 | 85.32 | 5.84 | 0.02 | ||||
200 | 83.40 | 11.41 | 87.00 | 2.57 | 0.41 | ||||
400 | 41.48 | 11.72 | 73.54 | 6.87 | < 0.0001 | ||||
72 h | Control | 100.18 | 0.32 | 331.4 ± 7.24 | 100.53 | 0.92 | > 400 | 0.56 | |
100 | 95.12 | 0.17 | 78.79 | 6.90 | 0.01 | ||||
200 | 83.83 | 1.65 | 76.2 | 7.92 | 0.23 | ||||
400 | 34.05 | 6.87 | 73.34 | 6.08 | < 0.0001 |