Table 2 Association between HIF1α expression scores and Clinico-pathological data of the studied cases; (N = 71)
Variables | Negative (19) | Score +1 (18) | Score +2 (23) | Score +3 (11) | Total 71 | P-value | |
|---|---|---|---|---|---|---|---|
Gender (N = 71) | Male | 9 (26.5%) | 8 (23.5%) | 10 (29.4%) | 7 (20.6%) | 34 | 0.689 |
Female | 10 (27.0%) | 10 (27.0%) | 13 (35.1%) | 4 (10.8%) | 37 | ||
Side (N = 71) | Right | 8 (28.6%) | 4 (14.3%) | 13 (46.4%) | 3 (10.7%) | 28 | 0.041* |
Left | 6 (18.8%) | 9 (28.1%) | 9 (28.1%) | 8 (25.0%) | 32 | ||
Midline | 5 (45.5%) | 5 (45.5%) | 1 (9.1%) | 0 (0.0%) | 11 | ||
Relation to tentorium cerebelli (N = 69)** | Supra-tentorial | 13 (22.0%) | 13 (22.0%) | 22 (37.3%) | 11 (18.6%) | 59 | 0.037* |
Infra-tentorial | 6 (60.0%) | 3 (30.0%) | 1 (10.0%) | 0 (0.0%) | 10 | ||
Recurrence (N = 71) | First time | 18 (30.50%) | 15 (25.40%) | 18 (30.50%) | 8 (13.60%) | 59 | 0.383 |
Recurrent | 1 (8.30%) | 3 (25.00%) | 5 (41.70%) | 3 (25.00%) | 12 | ||
Necrosis (N = 71) | Negative for necrosis | 13 (43.3%) | 11 (36.7%) | 6 (20.0%) | 0 (0.0%) | 30 | < 0.001* |
Positive for necrosis | 6 (14.6%) | 7 (17.1%) | 17 (41.5%) | 11 (26.8%) | 41 | ||
IDH1-R132H expression (N = 51) | Negative | 0 (0.0%) | 3 (15.8%) | 10 (52.6%) | 6 (31.6%) | 19 | 0.012* |
Positive | 11 (34.4%) | 8 (25.0%) | 8 (25.0%) | 5 (15.6%) | 32 |