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Table 4 Ovarian histomorphometric analysis of PCOS treated with l-Carnitine or Clomiphene citrate

From: Dysregulation of intraovarian redox status and steroidogenesis pathway in letrozole-induced PCOS rat model: a possible modulatory role of l-Carnitine

Parameters

C

PCOS

PCOS + LC

PCOS + CLO

Number of ovarian cysts

3.33 ± 1.53a

17.67 ± 1.45b

7.00 ± 1.00ac

8.00 ± 1.00d

Diameter of ovarian cysts

244.42 ± 38.97a

453.25 ± 80.61b

239.9 ± 44.1ac

438.55 ± 168.24db

Granulosa cell layer thickness

70.42 ± 29.72a

35.22 ± 4.83b

36.3 ± 6.15cb

31.36 ± 1.04dbc

Theca layer thickness

21.93 ± 5.65a

16.02 ± 0.63b

13.41 ± 0.77cb

14.83 ± 0.24dbc

  1. a,b,c,dMeans with different superscripts within the same row differ significantly at P < 0.05. No cysts observed in the control group, so all data related to normal ovarian follicles