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Table 3 The prediction of protein annotation pathways of a C. longa miRNAs targets using the STRING tool

From: Employing in silico investigations to determine the cross-kingdom approach for Curcuma longa miRNAs and their human targets

ID

KEGG description

Matching proteins in network

hsa01521

EGFR tyrosine kinase inhibitor resistance

GAB1, EGFR, MET, GRB2

hsa04360

Axon guidance

NTN1, MET, PTPN11, PPP3R2, DCC

hsa05205

Proteoglycans in cancer

GAB1, EGFR, MET, PTPN11, GRB2

hsa05211

Renal cell carcinoma

GAB1, MET, PTPN11, GRB2

hsa04014

Ras signalling pathway

GAB1, EGFR, MET, PTPN11, GRB2

hsa04072

Phospholipase D signalling pathway

GAB1, EGFR, PTPN11, GRB2

hsa05226

Gastric cancer

GAB1, EGFR, MET, GRB2

hsa05225

Hepatocellular carcinoma

GAB1, EGFR, MET, GRB2

hsa05120

Epithelial cell signalling in Helicobacter pylori infection

EGFR, MET, PTPN11

hsa05223

Non-small cell lung cancer

EGFR, MET, GRB2

hsa04012

ErbB signalling pathway

GAB1, EGFR, GRB2

hsa05210

Colorectal cancer

EGFR, GRB2, DCC

hsa05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

EGFR, PTPN11, PPP3R2

hsa05215

Prostate cancer

EGFR, ETV5, GRB2

hsa04722

Neurotrophin signalling pathway

GAB1, PTPN11, GRB2

hsa04650

Natural killer cell-mediated cytotoxicity

PTPN11, PPP3R2, GRB2

hsa04010

MAPK signalling pathway

EGFR, MET, PPP3R2, GRB2

hsa04068

FoxO signalling pathway

SETD7, EGFR, GRB2

hsa04630

JAK-STAT signalling pathway

EGFR, PTPN11, GRB2

hsa05206

MicroRNAs in cancer

EGFR, MET, GRB2

hsa05144

Malaria

KLRB1, MET