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Table 3 Distribution of SNPs in the NME1 gene for the two groups of patient responders and nonresponders

From: The relation between SNPs in the NME1 gene and response to sofosbuvir in Egyptian patients with chronic HCV

Groups

rs2302254 C/T

CC

CT

TT

P value

C

T

P value

Responders N = 71

39 (54.9%)

26 (36.6%)

6 (8.5%)

0.847

104 (73.2%)

38 (26.8%)

0.581

Non-responders N = 65

38 (58.4%)

23 (35.4%)

4 (6.2%)

 

99 (76.2%)

31 (23.8%)

 

Groups

rs16949649 T/C

CC

TC

TT

P value

C

T

P value

Responders N = 71

17 (23.9%)

38 (53.6%)

16 (22.5%)

0.937

72 (50.7%)

70 (49.3%)

0.792

Non-responders N = 65

16 (24.6%)

36 (55.4%)

13 (20.0%)

 

68 (52.3%)

62 (47.7%)

 
  1. N = number of patients, p ≥ 0.05 was considered nonsignificant