Fig. 1From: Association of genetic polymorphism of NUDT15, TPMT and ITPA gene in the toxicity and efficacy of azathioprine-based regimen in Egyptian inflammatory bowel disease patientsAZA metabolic pathway mediated by TPMT and NUDT15. AZA azathioprine, GST glutathione-Stransferase, 6-MP 6-mercaptopurine, XDH xanthine oxidase enzyme, 6TUA thiouric acid, HPRT hypoxanthine phosphoribosyltransferase, TIMP thioinosine monophosphate, TPMT thiopurine methyltransferase, MeMP methylmercaptopurine, MeTIMP methylthioinosine [12]Back to article page