Table 4 Association of studied SNPs with time to failure
| Â | Genotypes | p | |||
|---|---|---|---|---|---|
Wild | Heterozygous | Mutant | |||
rs1127354 | 5-year failure cumulative rate (%) | 26.9 | 35.7 | 100 | 0.216 |
| Â | time to failure (months) | mean | 112 | 75.9 | 36 |
95% CI | 91.9–132 | 58.7–93 | 36–36 | ||
rs1800460 | 5-year failure cumulative rate (%) | 25.9 | 100 | – | 0.003 |
time to failure (months) | mean | 112.8 | 40 | – | |
95% CI | 92.9–132.7 | 19.3–60.7 | – | ||
time to failure (months) | mean | 114.7 | 106.6 | 105 | |
95% CI | 85.1–144.3 | 79.5–133.7 | 40.2–169.8 | ||