Fig. 10

Histopathological examination of individual organs from TRV-treated groups. (a) Control. A Photomicrograph of liver in Wistar albino rats: Control group showed normal liver lobule architecture with central vein (v), normal hepatocytes, blood sinusoids and central vein. B Control group showed normal spleen with central artery, splenic cords (red pulp), lymphatic nodule (white pulp) and capsule. C Control group showed normal kidney with glomerulus (arrow), papillary ducts and capillaries. (b) Group I—low dose (10 mg/kg b.w.). B Photomicrograph of liver in Wistar albino rats: Low dose (10 mg/kg b.w) showed normal liver lobule architecture with central vein (v), normal hepatocytes, blood sinusoids and central vein. B Control group showed normal spleen with central artery, splenic cords (red pulp), lymphatic nodule (white pulp) and capsule. C Control group showed normal kidney with glomerulus (arrow), papillary ducts and capillaries. (c) Group II—mid-dose (20 mg/kg b.w.). C Photomicrograph of liver in Wistar albino rats: Mid-dose (20 mg/kg b.w) showed normal liver lobule architecture with central vein (v), normal hepatocytes, blood sinusoids and central vein. B Control group showed normal spleen with central artery, splenic cords (red pulp), lymphatic nodule (white pulp) and capsule. C Control group showed normal kidney with glomerulus (arrow), papillary ducts and capillaries. d) Group III—high dose (40 mg/kg b.w.). D Photomicrograph of liver in Wistar albino rats: High dose (40 mg/kg b.w) showed normal liver lobule architecture with central vein (v), normal hepatocytes, blood sinusoids and central vein. B Control group showed normal spleen with central artery, splenic cords (red pulp), lymphatic nodule (white pulp) and capsule. C Control group showed normal kidney with glomerulus (arrow), papillary ducts and capillaries